Ttc9a
WebTTC9A through estradiol action in emotional control. Although we know that Ttc9a-/- induces anxiety-like behavior through the effect of estradiol on serotonergic system 9, the possible mechanisms of TTC9A on estradiol and neuroplasticity-related changes remain obscure. In this study, we investigated the effects of TTC9A and estradiol WebSep 14, 2012 · 1. Introduction. Tetratricopeptide repeat domain 9A (TTC9A) is a member of TTC9 family proteins that also include TTC9B and TTC9C. Human TTC9A gene was first identified by sequence analysis of a cDNA clone from a brain cDNA library .It was confirmed to code for a 222 amino acid TTC9A protein in human using mouse polyclonal antibody …
Ttc9a
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WebPrimePCR™ Template for Probe Assay: TTC9, Human Reaction: 200 x 20 µl reactions Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay. WebSep 6, 2024 · It is plausible therefore that TTC9A negatively regulates ERalpha activity through interacting with co-chaperone proteins such as FKBP38 and FKBP51. TTC9A acts as a chaperone protein to facilitate the function of tropomyosins (including Tm5NM-1) in stabilizing microfilament and it may play a role in cancer cell invasion and metastasis
Web15 rows · Mar 21, 2024 · GeneCards Summary for TTC9 Gene. TTC9 (Tetratricopeptide Repeat Domain 9) is a Protein Coding gene. Diseases associated with TTC9 include Large … WebTetratricopeptide repeat domain 9A (TTC9A) is a target gene of estrogen and progesterone. It is over-expressed in breast cancer. However, little is known about the physiological …
WebTTC9A deficient mammary gland showed significant increase in mammary ductal elongation and branching on estrogen and progesterone treatment, demonstrating aberration in hormone receptor signaling in absence of TTC9A.These observations suggest that TTC9A negatively regulates mammary gland development and the possibility that … WebThe involvement of tetratricopeptide repeat domain 9A (TTC9A) deficiency in anxiety-like responses and behavioral despair through estradiol action on the serotonergic system …
WebTTC9A to be 222 aa. Using mouse polyclonal antibody generated against TTC9A protein, TTC9A was shown to be ubiquitously expressed in human tissues. In breast cancer cells, TTC9A was predominantly concentrated to the endoplasmic reticulum and was regulated by a number of factors, such as growth factors, serum factors and steroid hormones [2].
WebDownload scientific diagram Truncation constructs of TTC9A protein and their relative binding to Tm5NM-1 based on co-immunoprecipitation experiment. from publication: … forecast farmington mnWebEmerging evidence suggests that estradiol is a potent modulator of neuroplasticity. As estradiol and neuroplasticity changes are both implicated in mood regulation, and estradiol activity is negatively regulated by TTC9A, we hypothesized that the behavioral changes induced by Ttc9a-/- is also mediated by neuroplasticity-related mechanisms. forecast farmington moWebApr 1, 2024 · In brief, Ttc9a-/-and wildtype female mice were subjected to ovariectomy (OVX) as reported (Lim et al., 2016; Lin et al., 2001). After a 10-day recovery period, mice were administered a subcutaneous injection of either 10 μg/kg 17-β-estradiol benzoate . Effects of Ttc9a-/-and estradiol modulation on tail suspension immobility forecast fayetteville gaWebUniProtKB unreviewed (TrEMBL) Organism. Catharus fuscescens (Veery) Amino acids. 181. Protein existence. Predicted. Annotation score. 1/5. forecast fascist futureWebFeb 27, 2015 · Tetratricopeptide repeat domain 9A (TTC9A) is a target gene of estrogen and progesterone.It is over-expressed in breast cancer. However, little is known about the physiological function of TTC9A.The objectives of this study were to establish a Ttc9a knockout mouse model and to study the consequence of Ttc9a gene inactivation. The … forecast fcWebTTC9A through estradiol action in emotional control. Although we know that Ttc9a-/- induces anxiety-like behavior through the effect of estradiol on serotonergic system 9, the … forecast farmington nmWebApr 1, 2024 · We aimed to investigate the interactive roles of TTC9A and estradiol modulation on behavioral neuroplasticity. The tail suspension immobility data and brain … forecast fayetteville